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Recombinant Lyssavirus Rabies Glycoprotein, N-His
Product Overview
BioVenic's Recombinant Lyssavirus Rabies Glycoprotein, N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 51.6 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
The Lyssavirus Rabies glycoprotein is a key component of the virus, responsible for mediating entry into host cells by binding to specific receptors. It is the primary target for neutralizing antibodies and is used in the development of vaccines to induce immunity against rabies. In veterinary medicine, it is crucial for creating diagnostic tests and vaccines that protect animals from the fatal disease.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
References
- Ng, Weng M, et al. Structure of trimeric pre-fusion rabies virus glycoprotein in complex with two protective antibodies.Cell Host & Microbe. 2022, 30 (9): 1219-1230.e7.