Recombinant Mouse Fc Receptor-like Protein 1 (FCRL1), C-His

Mouse Fc Receptor-like Protein 1, or FCRL1, is a protein similar to Fc receptors, involved in immune response regulation. In mouse studies, FCRL1 is explored for its roles in immune cell function and diseases. FCRL1 is expressed on various immune cells, including B cells and natural killer cells, and can modulate their activation and effector functions. The molecule has both activating and inhibitory functions, depending on the context and the specific receptors engaged. In B cells, FCRL1 may regulate antibody production and class switching, while in natural killer cells, it can influence cytotoxicity and cytokine secretion. Research on FCRL1 has also implicated it in the pathogenesis of certain autoimmune diseases and infections, where dysregulated FCRL1 signaling may contribute to aberrant immune responses. Additionally, FCRL1 has been identified as a potential therapeutic target in cancer immunotherapy, as modulating its activity could enhance the antitumor functions of immune cells. Understanding the diverse roles of FCRL1 in different immune cell populations and disease settings is essential for developing targeted immunomodulatory therapies.