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Recombinant Canine Collagen Alpha-2(I) Chain (COL1A2), N-His-GST

Cat. No.AP1C103

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Canine Collagen Alpha-2(I) Chain (COL1A2), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 60.9 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Canine
Expression System E.coli
Purity >90% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight 60.9 kDa
Molecular Weight 61.0 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Target Information

Canine collagen alpha-2(I) chain is a component of type I collagen, which is essential for the structural integrity of various connective tissues in dogs, including skin, tendons, and bones. This chain, along with two alpha-1(I) chains, forms the triple helix structure of type I collagen, providing strength and support to these tissues. It plays a critical role in tissue development, repair, and maintenance, and its proper function is vital for overall canine health. Mutations in the gene encoding this protein can lead to connective tissue disorders in dogs, similar to osteogenesis imperfecta in humans.

Protein Canine Collagen Alpha-2(I) Chain (COL1A2)
Protein Synonym COL1-A2; OI4; Collagen Alpha-2(I)chain; osteogenesis imperfecta type IV; Collagen Of Skin;Tendon And bone;Alpha-2 Chain
Gene ID 403824
UniProt ID O46392

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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