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Recombinant Canine Podoplanin (PDPN)
Product Overview
BioVenic's Recombinant Canine Podoplanin (PDPN) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 17.6 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
Canine podoplanin (PDPN) is a type I transmembrane sialoglycoprotein involved in cell migration and proliferation. It is highly expressed in various tissues, including lymphatic endothelial cells and renal podocytes. In canine tumors, PDPN overexpression is associated with malignancy and progression, making it a potential biomarker and therapeutic target. For example, in canine non-tonsillar squamous cell carcinoma (NTSCC), PDPN promotes cell proliferation, survival, and migration. Additionally, PDPN is involved in tumor-associated lymphangiogenesis and immune evasion, further highlighting its role in cancer progression.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.