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Recombinant Mouse Lymphocyte Activation Gene 3 Protein (LAG3), C-His

Cat. No.AP2C832

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Lymphocyte Activation Gene 3 Protein (LAG3), C-His is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 57.0 kDa. The purity is>90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System Human Cells
Purity >90%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 57.0 kDa
Physical State Lyophilized
Formulation 0.01 mol/L PBS (pH 7.2) containing 0.2% (w/v) Procline-300.

Target Information

Mouse Lymphocyte Activation Gene 3 Protein (LAG3) is an immune checkpoint molecule expressed on activated T cells and regulatory T cells. LAG3 interacts with major histocompatibility complex class II molecules, modulating T cell responses. It is a therapeutic target in cancer immunotherapy and autoimmune diseases. LAG3 functions to inhibit T cell activation and proliferation, preventing excessive immune responses. By targeting LAG3, therapies can either enhance anti-tumor immunity by releasing the brake on T cell activity or suppress pathogenic immune responses in autoimmune conditions.

Protein Mouse Lymphocyte Activation Gene 3 Protein (LAG3)
Protein Synonym LAG-3; Activation-induced cytidine deaminase-linked autoimmunity protein; CD223
Gene ID 16768
UniProt ID Q61790

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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