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Recombinant Ovine Tissue Inhibitors of Metalloproteinase 1 (TIMP1), N-His

Cat. No.AP7F24

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Ovine Tissue Inhibitors of Metalloproteinase 1 (TIMP1), N-His is a recombinant protein expressed from E.coli expression system. Its predicted molecular weight is 23.2 kDa. The purity is greater than 90% (SDS-PAGE). The endotoxin level is <1 EU/μg (LAL). It can be used as a positive control or as an immunogen.

Specifications

Type Recombinant Protein
Species Ovine
Expression System E.coli
Purity >90% (SDS-PAGE)
Endotoxin <1 EU/μg (LAL)
Predicted Molecular Weight 23.2 kDa
Molecular Weight 23 kDa
Physical State Lyophilized
Formulation PBS, pH 7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose.

Target Information

Tissue Inhibitors of Metalloproteinase 1 is encoded by the sheep gene TIMP1. TIMP-1 is a member of the TIMP family. It acts as a natural inhibitor of the matrix metalloproteinases (MMPs). It is a 30,000 molecular weight glycoprotein that complexes with and inhibits the activity of a family of extracellular matrix-degrading enzymes. Research has shown that the follicular fluid concentration of TIMP1 in sheep increases following a gonadotropin surge.

Protein Ovine Tissue Inhibitors of Metalloproteinase 1 (TIMP1)
Protein Synonym EPO; CLGI; EPA; HCI; Erythroid Potentiating Activity; Collagenase Inhibitor; Metalloproteinase inhibitor 1; Fibroblast collagenase inhibitor
Gene ID 443331
UniProt ID P50122

Shipping and Storage

This product is shipped with dry ice. Avoid repeated freezing and thawing. Store for 4 weeks at 2-8°C, for 12 months at -80°C.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH 7.4) to a concentration of 0.1-1.0 mg/mL. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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