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Recombinant Swine Beta-Defensin 1 (DEFB1), N-His
Product Overview
BioVenic's Recombinant Swine Beta-Defensin 1 (DEFB1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 11.1 kDa. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Swine beta-defensin 1 (DEFB1) is an antimicrobial peptide primarily expressed in epithelial cells, with broad-spectrum antimicrobial activity that resists colonization by various microorganisms. DEFB1 plays a crucial role in the epithelial surfaces of the respiratory tract, urogenital tract, and vagina in swine, protecting the host from infections. Additionally, DEFB1 is involved in immune regulation, promoting antigen-specific immune responses. In swine, research on DEFB1 helps to understand its role in disease defense, providing a basis for developing new therapeutic strategies. For example, DEFB1 is expressed in the intestinal epithelial cells of pigs, inhibiting pathogen adhesion and invasion, and enhancing intestinal barrier function.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.