This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Recombinant Mycobacterium tuberculosis CPF10 (CPF10), N-His
Product Overview
BioVenic's Recombinant Mycobacterium tuberculosis CPF10 (CPF10), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 17.5 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Mycobacterium tuberculosis CPF10 is a key immunodominant antigen that plays a significant role in the pathogenesis of tuberculosis. It is part of the ESX-1 secretion system and is essential for the virulence of the bacteria. CPF10 is also crucial for the secretion of ESAT-6, another important antigen, and the two often form a complex that modulates macrophage cell death, which is believed to be a strategy used by the bacteria to evade the host immune response. This protein is also used in diagnostic tests for tuberculosis, particularly in the interferon-gamma release assays (IGRAs), due to its strong immunogenicity.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.