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Native Bovine Cartilage Collagen Type II Alpha 1 (COL2A1)

Product Overview

BioVenic's Native Bovine Cartilage Collagen Type II Alpha 1 (COL2A1) is a native protein derived from Bovine Cartilage.

Specifications

Type Native Protein

Species Bovine

Source Cartilage

Purity >98% (SDS-PAGE)

Predicted Molecular Weight 142 kDa

Physical State Liquid

Formulation 0.5 M Acetic Acid, pH 4.5, 0.01% Sodium Azide.

Target Information

Collagen, type II, alpha 1 (COL2A1), also known as cartilage collagen, is a crucial protein involved in maintaining the structural integrity of various tissues. Bovine Collagen type II alpha 1 chain is encoded by the COL2A1 gene in cattle. Abnormalities in this gene have been associated with some cases of the bulldog calf syndrome. Research has found that a large deletion in the COL2A1 gene expands the spectrum of pathogenic variants causing bulldog calf syndrome in cattle.

Protein Bovine Collagen Type II Alpha 1 (COL2A1)

Protein Synonym collagen type II alpha 1 chain; CB11; collagen alpha-1(II) chain; alpha-1 type II collagen; collagen, type II, alpha 1; pro-alpha 1(II)

Gene ID 407142

UniProt ID P02459

Shipping and Storage

Store at 2-8°C for 1 year.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Jacinto, J. G. P. et al. A large deletion in the COL2A1 gene expands the spectrum of pathogenic variants causing bulldog calf syndrome in cattle. Acta veterinaria Scandinavica. 2020, 62: 49.