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Native Bovine Pancreas Deoxyribonuclease I (DNASE1)
Product Overview
BioVenic's Native Bovine Pancreas Deoxyribonuclease I (DNASE1) is a native protein derived from Bovine Pancreas.
Specifications
Target Information
Deoxyribonuclease 1 (DNase I), also known as DNase 1, is an endonuclease enzyme that plays a crucial role in cleaving the phosphodiester bonds within the DNA backbone. It acts as the molecular scissors, specifically targeting double-stranded DNA and breaking it down into smaller fragments. Deoxyribonuclease 1 is encoded by the DNASE1 gene in cattle. It is a nuclease of relatively low specificity which interacts with DNA in the minor groove.
Shipping and Storage
Store at -20°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Cal, S. et al. Conversion of bovine pancreatic DNase I to a repair endonuclease with a high selectivity for abasic sites. The EMBO journal. 1998, 17: 7128-7138.