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Recombinant Equine Insulin-Like Growth Factor II (IGF2), N-His
Product Overview
BioVenic's Recombinant Equine Insulin-Like Growth Factor II (IGF2), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Equine Insulin-like Growth Factor 2 (IGF-2) is a crucial player in various physiological processes, particularly in growth and development. It is known to promote tissue growth, lower blood sugar levels, and play a significant role in fetal development. IGF-2 can interact with IGF1R, IGF2R, and insulin receptor A/B (IR-A/B), where it activates IGF1R to stimulate growth and regulate cell proliferation, differentiation, and metabolism, and activates IR-A to promote mitosis and IR-B to promote metabolism. Moreover, IGF-2 has been implicated in metabolic diseases and is involved in the regulation of luteal function, potentially influencing progesterone production.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.