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Recombinant Canine Thrombopoietin (THPO), N-His-TRxA
Product Overview
BioVenic's Recombinant Canine Thrombopoietin (THPO), N-His-TRxA is a recombinant protein expressed from E.coli. Its predicted molecular weight is 55.4 kDa. The purity is>80% (SDS-PAGE).
Specifications
Target Information
Canine thrombopoietin is a cytokine that plays a critical role in the regulation of platelet production, or thrombopoiesis. It stimulates the development of megakaryocytes, the cells responsible for platelet formation in the bone marrow. Thrombopoietin is essential for maintaining platelet counts in the bloodstream and is used therapeutically to treat conditions like immune-mediated thrombocytopenia (ITP) in dogs, where platelet destruction is immune-mediated. It can help increase platelet counts and improve clinical outcomes in dogs with severe and refractory ITP.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.