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Mouse Anti-Canine Adenovirus (CAV) Monoclonal Antibody-Detection
Product Overview
BioVenic mouse monoclonal antibody is specific for canine adenovirus. It can be applied to ICA and IF of canine adenovirus. The clone L13N25 can be used as capture antibody and the L13N26 can be used as detection antibody in the assay.
Specifications
Target Information
Canine adenoviruses (CAVs) are a group of non-enveloped viruses that can cause respiratory and gastrointestinal diseases in dogs. The target information for CAVs typically focuses on their capsid proteins, which are crucial for viral attachment and entry into host cells. The hexon, penton base, and fiber proteins are the primary structural components of the CAV capsid, providing potential targets for vaccine development and antiviral therapies. The hexon is the most abundant protein and forms the 20-sided capsid shell, offering a large surface area for immune recognition and neutralization. The penton base, located at the vertices of the capsid, interacts with cellular receptors during viral entry. The fiber protein projects from the penton base and is responsible for initial attachment to host cells, making it a key player in host specificity and pathogenesis.
Shipping and Storage
This product is shipped at ambient temperature. Store at 4°C (up to 12 months) on receipt. Do not freeze.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Recommended pairs for sandwich immunoassay (capture-detection): L13N25-L13N26
References
- Zhu, Yanzhu, et al. "Difference analysis between canine adenovirus types 1 and 2." Frontiers in cellular and infection microbiology 12 (2022): 854876.