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Mouse Anti-Canine Adenovirus (CAV) Monoclonal Antibody-Detection

Cat. No.VD7N144

Product TypeVeterinary Antibodies

Product Overview

BioVenic mouse monoclonal antibody is specific for canine adenovirus. It can be applied to ICA and IF of canine adenovirus. The clone L13N25 can be used as capture antibody and the L13N26 can be used as detection antibody in the assay.

Specifications

Application ICA; IF
Clonality Monoclonal
Classification Primary Antibody
Clone L13N26
Host Mouse
Target Species Virus
Species Reactivity Canine
Specificity Canine Adenovirus
Isotype IgG1
Purity > 90%
Concentration 4 mg/mL
Conjugation Unconjugated
Physical State Liquid

Target Information

Canine adenoviruses (CAVs) are a group of non-enveloped viruses that can cause respiratory and gastrointestinal diseases in dogs. The target information for CAVs typically focuses on their capsid proteins, which are crucial for viral attachment and entry into host cells. The hexon, penton base, and fiber proteins are the primary structural components of the CAV capsid, providing potential targets for vaccine development and antiviral therapies. The hexon is the most abundant protein and forms the 20-sided capsid shell, offering a large surface area for immune recognition and neutralization. The penton base, located at the vertices of the capsid, interacts with cellular receptors during viral entry. The fiber protein projects from the penton base and is responsible for initial attachment to host cells, making it a key player in host specificity and pathogenesis.

Target Canine Adenovirus
Target Synonym CAV
Taxonomy ID 10537

Shipping and Storage

This product is shipped at ambient temperature. Store at 4°C (up to 12 months) on receipt. Do not freeze.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Recommended pairs for sandwich immunoassay (capture-detection): L13N25-L13N26

References

  1. Zhu, Yanzhu, et al. "Difference analysis between canine adenovirus types 1 and 2." Frontiers in cellular and infection microbiology 12 (2022): 854876.
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