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Mouse Anti-Canine Cytochrome C Monoclonal Antibody

Cat. No.VD11N169

Product TypeAnimal-targeted Antibodies

Size 100 μg

Product Overview

BioVenic mouse monoclonal antibody is specific for canine cytochrome C. It can be applied to WB, IHC and FACS assays of canine cytochrome C.

Specifications

Application WB; IHC; FACS
Clonality Monoclonal
Classification Primary Antibody
Clone S15N9
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Cytochrome C
Isotype IgG2
Immunogen Recombinant protein of cytochrome C
Concentration 0.2 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Sodium Azide
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Canine cytochrome C is a multifunctional protein that plays a pivotal role in cellular respiration and apoptosis. It is involved in electron transfer within the respiratory chain and acts as a detoxifying agent to dispose of reactive oxygen species (ROS). In the context of cell death, cytochrome C is released from the mitochondria into the cytosol, where it binds to APAF-1, activates pro-caspase 9, and initiates an enzymatic cascade leading to cell death. This protein's interaction with cardiolipin, a phospholipid in the mitochondrial membrane, is essential for initiating apoptosis and transforming cytochrome C's function from an electron-transfer shuttle to a peroxidase-like hemoprotein.

Target Canine Cytochrome C
Target Synonym CYCS; CYC
Gene ID 475258
UniProt ID P00011

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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