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Mouse Anti-Canine Peroxisomal Biogenesis Factor 5 (PEX5) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine peroxisomal biogenesis factor 5. It can be applied to WB; ICC/IF and FACS assays of canine peroxisomal biogenesis factor 5.
Specifications
Target Information
Canine peroxisomal biogenesis factor 5 (PEX5) is a critical peroxin protein that plays a central role in the biogenesis of peroxisomes, organelles involved in the metabolism of lipids and reactive oxygen species (ROS) management. PEX5 functions as a shuttling receptor for proteins containing a type 1 peroxisome targeting signal (PTS1), directing them to the peroxisomal matrix. It is essential for the import of PTS1 proteins into the peroxisomes and is involved in the regulation of pexophagy, the selective degradation of peroxisomes by autophagy. The downregulation of PEX5 has been associated with the modulation of apoptotic pathways, suggesting its importance in cellular survival and death mechanisms.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.