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Mouse Anti-Porcine APPL1 Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for APPL1. It is affinity purified by protein A. It can be applied to WB, IHC, IF/ICC, FC and ELISA assays of APPL1.
Specifications
Target Information
Porcine APPL1 (pAPPL1), also known as adaptor protein containing pleckstrin homology (PH) and domain and leucine zipper 1, is a multidomain adaptor protein that plays a pivotal role in intracellular signaling pathways in pigs. It is involved in the regulation of various cellular processes, including cell survival, growth, and metabolism. pAPPL1 is characterized by the presence of a PH domain, which allows it to bind to phospholipids and mediate membrane recruitment, as well as leucine-rich repeat motifs that are involved in protein-protein interactions. This protein is known to interact with a variety of signaling molecules, including those involved in the phosphoinositide 3-kinase (PI3K) and Akt signaling pathways.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Tu, Qisheng, et al. "Adiponectin inhibits osteoclastogenesis and bone resorption via APPL1-mediated suppression of Akt1." Journal of Biological Chemistry 286.14 (2011): 12542-12553.