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Mouse Anti-Canine Structural Maintenance of Chromosomes X-Linked (SMCX) Monoclonal Antibody

Cat. No.VD8N148

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for canine structural maintenance of chromosomes X-linked. It can be applied to WB, IF and ICC assays of canine structural maintenance of chromosomes X-linked.

Specifications

Application WB; IF; ICC
Clonality Monoclonal
Classification Primary Antibody
Clone G4N11
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Structural Maintenance of Chromosomes X-Linked
Isotype IgG
Immunogen Purified recombinant canine structural maintenance of chromosomes X-linked (C-terminus) protein fragments
Concentration 1 mg/mL
Conjugation Unconjugated
Physical State Liquid

Target Information

Structural maintenance of chromosomes X-linked (SMCX) is a multifunctional protein that plays a significant role in the maintenance of genomic integrity. SMCX is a member of the structural maintenance of chromosomes (SMC) family, which are essential for the proper segregation of chromosomes during cell division. As an ATPase, SMCX is involved in the dynamic regulation of chromatin structure, which facilitates processes such as DNA replication, repair, and recombination. It contributes to the formation and function of the cohesin complex, ensuring that sister chromatids remain attached until they are accurately distributed to daughter cells during cell division.

Target Canine Structural Maintenance of Chromosomes X-Linked
Target Synonym KDM5C; DXS1272E
Gene ID 491894
UniProt ID Q38JA7

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Akhmedov, Alexandre T., et al. "Structural maintenance of chromosomes protein C-terminal domains bind preferentially to DNA with secondary structure." Journal of Biological Chemistry 273.37 (1998): 24088-24094.
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