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Mouse Anti-Chicken β2 Microglobulin Monoclonal Antibody-[FITC]

Cat. No.VD7N302

Product TypeAnimal-targeted Antibodies

Size 0.5 mg

Product Overview

BioVenic mouse monoclonal antibody is specific for chicken β2 microglobulin. It can be applied to FCM, WB and IP assays of chicken β4 microglobulin.

Specifications

Application FCM; IP; WB
Clonality Monoclonal
Classification Primary Antibody
Clone L11N41
Host Mouse
Target Species Chicken
Species Reactivity Chicken; Avian
Specificity Chicken β2-Microglobulin
Isotype IgG1
Immunogen Chicken MHC-I molecules
Purity > 90%
Concentration 0.5 mg/mL
Conjugation FITC
Preservative and Stabilizer < 0.1% Sodium Azide
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Chicken β2-Microglobulin (β2M) is a small protein component that is universally expressed in the body and plays a critical role in the immune system of chickens. It is a part of the major histocompatibility complex (MHC) class I molecules, which are essential for the immune response by presenting endogenous antigens to CD8+ T cells. As an invariant chain, β2M associates with the heavy chain of MHC class I molecules, aiding in their transport to the cell surface. This presentation is crucial for the activation of cytotoxic T lymphocytes, which are responsible for identifying and eliminating cells infected with intracellular pathogens or damaged cells.

Target Chicken β2-Microglobulin
Target Synonym MHC Class I; B-F
Gene ID 414830; 100539873
UniProt ID P21611; P21612

Shipping and Storage

This product is shipped with ice gel packs. Store at 2°C - 8°C (up to 12 months) on receipt. Avoid exposure to light.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Stoppini, Monica, et al. "Systemic amyloidosis: lessons from β2-microglobulin." Journal of Biological Chemistry 290.16 (2015): 9951-9958.
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