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Mouse Anti-Porcine Clathrin Heavy Chain (CLTC) Monoclonal Antibody

Cat. No.VD8N309

Product TypeAnimal-targeted Antibodies

Size

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Product Overview

BioVenic mouse monoclonal antibody is specific for clathrin heavy chain. It is affinity purified by protein A. It can be applied to WB, IF/ICC, IHC and ELISA assays of clathrin heavy chain.

Specifications

Application WB; IHC; IF/ICC; ELISA

Clonality Monoclonal

Classification Primary Antibody

Clone G6N53

Host Mouse

Target Species Porcine

Species Reactivity Porcine

Specificity Clathrin Heavy Chain

Isotype IgG1

Immunogen Recombinant protein of clathrin heavy chain

Purification Protein A Purified

Concentration 1500 μg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.02% Sodium Azide

Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3

Physical State Liquid

Target Information

Porcine clathrin heavy chain (CHC) is a fundamental component of the clathrin-coated vesicles, which are essential in the process of receptor-mediated endocytosis in pigs. CHC, along with clathrin light chains, forms a polyhedral lattice that surrounds the vesicle, providing the structural framework necessary for the vesicle's assembly, cargo selection, and budding from the plasma membrane. This protein plays a critical role in the internalization of nutrients, signaling molecules, and the regulation of cell surface receptors. CHC is also involved in the trafficking of proteins within the cell, including the transport between the trans-Golgi network and endosomes.

Target Clathrin Heavy Chain

Gene ID 100271929

UniProt ID C0MHR2

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Hinrichsen, Lars, et al. "Effect of clathrin heavy chain-and α-adaptin-specific small inhibitory RNAs on endocytic accessory proteins and receptor trafficking in HeLa cells." Journal of Biological Chemistry 278.46 (2003): 45160-45170.