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Mouse Anti-Porcine Complement Factor Properdin (CFP) Monoclonal Antibody

Cat. No.VD8N489

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for complement factor properdin. It is affinity purified by protein G. It can be applied to WB and ELISA assays of complement factor properdin.

Specifications

Application WB; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G10N37
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Complement Factor Properdin
Isotype IgG1
Immunogen Recombinant protein of complement factor properdin
Purification Protein G Purified
Concentration 1200 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine complement factor properdin, also known as C3b binding protein or FBLN1, is a crucial component of the alternative pathway of the complement system, which is a part of the innate immune response. Properdin stabilizes the C3 convertase of the alternative pathway, thereby enhancing the deposition of C3b on pathogen surfaces and promoting opsonization and complement-mediated lysis. As a molecular target, Properdin is significant due to its role in modulating the immune response to infections. It is particularly important in the defense against a variety of pathogens, including bacteria, viruses, and parasites. Given its central function in the complement system, Properdin represents a potential therapeutic target for conditions where complement dysregulation contributes to disease pathogenesis, such as autoimmune diseases and age-related macular degeneration.

Target Complement Factor Properdin
Target Synonym BFD; CFP
Gene ID 100522293
UniProt ID P04404

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Kouser, Lubna, et al. "Properdin and factor h: opposing players on the alternative complement pathway "see-saw"." Frontiers in immunology 4 (2013): 93.
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