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Mouse Anti-Porcine Complement Factor Properdin (CFP) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for complement factor properdin. It is affinity purified by protein G. It can be applied to WB and ELISA assays of complement factor properdin.
Specifications
Target Information
Porcine complement factor properdin, also known as C3b binding protein or FBLN1, is a crucial component of the alternative pathway of the complement system, which is a part of the innate immune response. Properdin stabilizes the C3 convertase of the alternative pathway, thereby enhancing the deposition of C3b on pathogen surfaces and promoting opsonization and complement-mediated lysis. As a molecular target, Properdin is significant due to its role in modulating the immune response to infections. It is particularly important in the defense against a variety of pathogens, including bacteria, viruses, and parasites. Given its central function in the complement system, Properdin represents a potential therapeutic target for conditions where complement dysregulation contributes to disease pathogenesis, such as autoimmune diseases and age-related macular degeneration.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Kouser, Lubna, et al. "Properdin and factor h: opposing players on the alternative complement pathway "see-saw"." Frontiers in immunology 4 (2013): 93.