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Mouse Anti-Porcine Ras-Related Protein Rab-5A (RAB5A) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for ras-related protein rab-5A. It is affinity purified by protein A. It can be applied to WB, IF, IHC and ELISA assays of ras-related protein rab-5A.
Specifications
Target Information
Porcine ras-related protein rab-5A is a member of the Rab family of small GTPases, which are crucial regulators of vesicular traffic within cells. Rab-5A plays a pivotal role in the early stages of the endocytic pathway, facilitating the formation of endosomes and regulating the fusion of vesicles with the plasma membrane. This protein is highly conserved across species, including pigs, and is essential for the proper functioning of the endosomal system, which is involved in the internalization of nutrients, signaling molecules, and the processing of cellular waste. Rab-5A's activity is tightly regulated by a cycle of GTP binding and hydrolysis, which controls its interaction with various effector proteins.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Sung, Jee Young, et al. "Induction of neuronal cell death by Rab5A-dependent endocytosis of α-synuclein." Journal of Biological Chemistry 276.29 (2001): 27441-27448.