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Mouse Anti-Canine DNA-Binding Protein Ikaros (IKZF1) Monoclonal Antibody

Cat. No.VD12N406

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine DNA-binding protein ikaros. It is purified by affinity chromatography. It can be applied to WB assay of canine DNA-binding protein ikaros.

Specifications

Application WB
Clonality Monoclonal
Classification Primary Antibody
Clone M5N20
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine DNA-Binding Protein Ikaros
Immunogen Recombinant protein of DNA-binding protein ikaros
Purification Purified by Affinity Chromatography
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer 0.1M Tris-Glycine, pH 7.4, with 150 mM NaCl and 50% glycerol
Physical State Liquid

Target Information

Canine DNA-Binding Protein Ikaros (IKZF1) is a transcriptional regulator crucial for hematopoietic cell differentiation and lymphocyte development. It belongs to the zinc-finger protein family and binds to gamma-satellite DNA, playing a key role in the development of B- and T-cells. Ikaros is also involved in the regulation of gene expression and chromatin organization, with its N-terminal zinc fingers required for DNA binding and targeting to heterochromatin. Mutations in Ikaros have been associated with B-cell acute lymphoblastic leukemia (B-ALL) and other hematologic malignancies.

Target Canine DNA-Binding Protein Ikaros
Target Synonym IKZF1
Gene ID 483231
UniProt ID A0A8I3RVH8

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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