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Mouse Anti-Porcine Structural Maintenance of Chromosomes 1 (SMC1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for porcine structural maintenance of chromosomes 1. It can be applied to WB, IHC, IF and FCM assays of porcine structural maintenance of chromosomes 1.
Specifications
Target Information
Structural maintenance of chromosomes 1 (SMC1) is a crucial protein involved in the maintenance and proper segregation of sister chromatids during cell division. As part of the cohesin complex, SMC1 plays a vital role in chromosome cohesion, which ensures that duplicated chromosomes stay connected until they are correctly segregated during mitosis. SMC1's function is essential for preventing aneuploidy, a condition where cells have an abnormal number of chromosomes, which can lead to developmental disorders and cancer. The protein is involved in various aspects of DNA metabolism, including DNA repair, recombination, and replication.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Akhmedov, Alexandre T., et al. "Structural maintenance of chromosomes protein C-terminal domains bind preferentially to DNA with secondary structure." Journal of Biological Chemistry 273.37 (1998): 24088-24094.