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Rabbit Anti-Porcine Complement C5 Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for porcine complement C5. It is affinity purified by protein G. It can be applied to ELISA assay of porcine complement C5.
Specifications
Target Information
Porcine complement C5 is a key component of the complement system, an essential part of the innate immune system in pigs. Its activation leads to the cleavage of C5 into two fragments, C5a and C5b. C5a acts as an anaphylatoxin, binding to C5aR and inducing a range of biological responses, while C5b initiates the formation of the membrane attack complex (MAC), capable of killing susceptible pathogens by pore formation in association with C6, C7, C8, and C9.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Pischke, Soeren E., et al. "Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function." Basic research in cardiology 112 (2017): 1-14.