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Mouse Anti-Porcine Gastrokine 1 Monoclonal Antibody

Cat. No.VD8N521

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for gastrokine 1. It is affinity purified by protein A. It can be applied to WB, IF, IHC and ELISA assays of gastrokine 1.

Specifications

Application WB; IF; IHC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G11N18
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Gastrokine 1
Isotype IgG2
Immunogen Recombinant protein of gastrokine 1
Purification Protein A Purified
Concentration 1500 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine gastrokine 1 (GKN1), analogous to its human counterpart, is a mucin-like protein that is predominantly expressed in the gastric mucosa. GKN1 plays a crucial role in the protection and maintenance of the gastric mucosal barrier, which is essential for the defense against acidic gastric juice, pepsin, and other potentially damaging agents. As a molecular target, GKN1 is significant due to its involvement in the gastric mucosal defense mechanism and its potential implications in the pathogenesis of gastric disorders, such as gastritis, peptic ulcer disease, and gastric cancer. Understanding the function of GKN1 in the gastric mucosa could provide insights into the development of therapeutic strategies for the treatment and prevention of these conditions.

Target Gastrokine 1
Target Synonym 18 kDa antrum mucosa protein; AMP 18
Gene ID 100621719
UniProt ID Q8HYA9

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Yoon, Jung Hwan, et al. "Gastrokine 1 protein is a potential theragnostic target for gastric cancer." Gastric Cancer 21 (2018): 956-967.
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