Mouse Anti-Porcine Phospholipase A2 Group Ib (PLA2G1B) Monoclonal Antibody

Porcine phospholipase A2 group Ib (PLA2G1B) is an enzyme that belongs to the phospholipase A2 (PLA2) superfamily, which is known for its role in hydrolyzing the sn-2 ester bond of phospholipids. This process is crucial as it releases free fatty acids and lysophospholipids, which are essential for various cellular functions, including cell signaling, membrane remodeling, and energy metabolism. In pigs, PLA2G1B may play a role in inflammatory responses and lipid metabolism, similar to its function in humans. The PLA2 enzymes, including Group Ib, are amphiphilic and require interaction with the water-lipid interface for their activity. They are involved in the generation of lipid second messengers and the hydrolysis of phospholipid assemblies, rather than isolated single phospholipids.