Mouse Anti-Porcine Sestrin 2 Monoclonal Antibody

Porcine sestrin 2 is a stress-responsive protein that plays a crucial role in cellular metabolism and stress resistance. It is known for its antioxidant properties and its ability to regulate the mammalian target of rapamycin (mTOR) signaling pathway, which is a key controller of cell growth and metabolism. In pigs, sestrin 2 has been correlated with the unfolded protein response (UPR) and endoplasmic reticulum (ER) stress, indicating its involvement in the cellular response to various stressors, including oxidative stress and ER stress. The protein has also been implicated in the regulation of oocyte maturation, where its expression is associated with the stress mediator response to ER stress through the PERK signaling pathways.