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Rabbit Anti-Bovine L-2-Hydroxyglutarate Dehydrogenase (L2HGDH) Polyclonal Antibody-[HRP]

Cat. No.VD11N651

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for bovine L-2-hydroxyglutarate dehydrogenase. It is affinity purified by protein G. It can be applied to ELISA assay of bovine L-2-hydroxyglutarate dehydrogenase.

Specifications

Application ELISA
Clonality Polyclonal
Classification Primary Antibody
Clone J6N32
Host Rabbit
Target Species Bovine
Species Reactivity Bovine
Specificity Bovine L-2-Hydroxyglutarate Dehydrogenase
Isotype IgG
Immunogen Recombinant protein of L-2-hydroxyglutarate dehydrogenase
Purification Protein G Purified
Purity > 95%
Conjugation HRP
Preservative and Stabilizer 0.03% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Bovine L-2-hydroxyglutarate dehydrogenase (L2HGDH) is a mitochondrial enzyme that catalyzes the oxidation of L-2-hydroxyglutarate (L-2-HG) to α-ketoglutarate (α-KG). This enzyme plays a crucial role in cellular metabolism and is involved in maintaining the balance of metabolic pathways. Mutations in L2HGDH can lead to the accumulation of L-2-HG, resulting in a neurometabolic disorder known as L-2-hydroxyglutaric aciduria (L-2-HGA), which is characterized by cognitive impairment.

Target Bovine L-2-Hydroxyglutarate Dehydrogenase
Target Synonym L2HGDH
Gene ID 514230
UniProt ID A7MBI3

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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