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Rabbit Anti-Canine IL-1-beta Polyclonal Antibody

Cat. No.VD12Q4

Product TypeAnimal-targeted Antibodies

Size 100 µL

Product Overview

BioVenic rabbit anti-canine IL-1-beta polyclonal antibody is specific for canine IL-1-beta. It was produced in rabbit hybridoma and protein A purified. It can be applied to ELISA and western blot assay.

Specifications

Application ELISA; WB
Clonality Polyclonal Antibody
Clone D7Q7
Host Rabbit
Target Species Canine
Species Reactivity Canine
Specificity Canine IL-1-beta
Isotype IgG
Immunogen Recombinant Canine IL-1-beta Protein
Purification Protein A Purified
Purity ≥ 95% (SDS-PAGE)
Conjugation Unconjugated
Buffer Phosphate buffered saline
Physical State Liquid

Target Information

Canine IL-1-beta (interleukin-1 beta) is an important cytokine involved in various cellular responses and signaling pathways. It enables cytokine activity and interleukin-1 receptor binding, playing a crucial role in the immune system, inflammatory response, and regulation of gene expressions. IL-1-beta is involved in certain canine diseases, including chronic degenerative valvular disease, inflammatory bowel disease, and pulmonary hemorrhage in leptospirosis. It is significantly up-regulated in these conditions, indicating its impact on the body's response to diseases. Canine IL-1-beta is found in extracellular space, molding the cellular environment for reaction against inflammatory changes.

Target Canine IL-1-beta
Target Synonym interleukin-1 beta; interleukin-1 beta proprotein
Gene ID 403974
UniProt ID Q28292

Shipping and Storage

This product is shipped with dry ice. Store at -20°C to -80°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Tan, Andrea R., et al. "Cytokine preconditioning of engineered cartilage provides protection against interleukin-1 insult." Arthritis Research & Therapy 17 (2015): 1-12.
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