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Rabbit Anti-Canine IL-1-beta Polyclonal Antibody
Product Overview
BioVenic rabbit anti-canine IL-1-beta polyclonal antibody is specific for canine IL-1-beta. It was produced in rabbit hybridoma and protein A purified. It can be applied to ELISA and western blot assay.
Specifications
Target Information
Canine IL-1-beta (interleukin-1 beta) is an important cytokine involved in various cellular responses and signaling pathways. It enables cytokine activity and interleukin-1 receptor binding, playing a crucial role in the immune system, inflammatory response, and regulation of gene expressions. IL-1-beta is involved in certain canine diseases, including chronic degenerative valvular disease, inflammatory bowel disease, and pulmonary hemorrhage in leptospirosis. It is significantly up-regulated in these conditions, indicating its impact on the body's response to diseases. Canine IL-1-beta is found in extracellular space, molding the cellular environment for reaction against inflammatory changes.
Shipping and Storage
This product is shipped with dry ice. Store at -20°C to -80°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Tan, Andrea R., et al. "Cytokine preconditioning of engineered cartilage provides protection against interleukin-1 insult." Arthritis Research & Therapy 17 (2015): 1-12.