Rabbit Anti-Equine Apolipoprotein C2 (APOC2) Polyclonal Antibody

Equine apolipoprotein C2 (APOC2) is a key player in lipid metabolism, particularly in the hydrolysis of triglycerides. It serves as a cofactor for lipoprotein lipase (LPL), facilitating the entry of triglycerides into the LPL active site and promoting their hydrolysis. This process is crucial for the clearance of triglyceride-rich lipoproteins, such as chylomicrons and very-low-density lipoproteins (VLDL). APOC2 is associated with these lipoproteins and is involved in their metabolism, helping to regulate lipid levels in the bloodstream. Mutations in the APOC2 gene can lead to significantly elevated triglyceride levels due to impaired clearance of triglyceride-rich lipoproteins , highlighting the importance of APOC2 in maintaining cardiovascular health in horses.