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Recombinant African Swine Fever Virus I9R (I9R CDS), N-His-SUMO
Product Overview
BioVenic's Recombinant African Swine Fever Virus I9R (I9R CDS), N-His-SUMO is a recombinant protein expressed from E.coli. Its predicted molecular weight is 23.8 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
African swine fever virus I9R (I9R CDS) is an early viral gene that plays a significant role in the replication cycle of ASFV. It has been identified as a key virulence factor that suppresses the host innate immune response by inhibiting the synthesis of host proteins, including antiviral proteins. The protein is a nucleic-acid-binding protein containing a Zα domain, which localizes in the nucleus and inhibits host protein synthesis by suppressing the nuclear export of cellular messenger RNA (mRNAs). This function is crucial for viral replication and pathogenesis, making I9R a potential target for virus attenuation and a candidate for developing live-attenuated vaccines.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.