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Recombinant Borrelia afzelii Flagellin, N-His-TrxA
Product Overview
BioVenic's Recombinant Borrelia afzelii Flagellin, N-His-TrxA is a recombinant protein expressed from E.coli. Its predicted molecular weight is 25.6 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Borrelia afzelii flagellin is a flagellar protein found in Borrelia afzelii, a spirochete that causes Lyme disease. It is a major structural component of the flagellum, composed of 20,000 to 30,000 helically arranged flagellin units. The molecular size of flagellin ranges from 20 to 60 kDa, and they spontaneously assemble into hollow cylinders with an inner diameter of about 2 nm and an outer diameter of 20 nm. In mammals, flagellin can bind to Toll-like receptor 5 (TLR5), activating the innate immune response in epithelial and dendritic cells, and also stimulating the formation of T helper cells in the adaptive immune response.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.