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Recombinant Clostridium perfringens Beta-2 toxin (cpb2), N-His
Product Overview
BioVenic's Recombinant Clostridium perfringens Beta-2 toxin (cpb2), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 30.0 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
The role and function of Clostridium perfringens Beta-2 toxin (cpb2) in the field of veterinary medicine are primarily as a significant virulence factor causing enteric diseases in animals. This toxin can form highly cation-selective channels, leading to cell apoptosis, increased inflammatory responses, and the disruption of intestinal barrier function. Specifically, Beta-2 toxin induces apoptosis in porcine intestinal epithelial cells, increases the expression of pro-inflammatory cytokines, and causes cell injury. Moreover, the toxin is associated with necrotizing enterocolitis and enterotoxemia in various animal species.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.