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Recombinant Bovine Apoptosis Regulator Bcl-2 (BCL2), N-His
Product Overview
BioVenic's Recombinant Bovine Apoptosis Regulator Bcl-2 (BCL2), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Bovine apoptosis regulator Bcl-2, encoded by the BCL2 gene, is a member of the Bcl-2 family of proteins. It acts as an inhibitor of apoptosis, playing a critical role in the regulation of programmed cell death. This protein is particularly important in the development of liver tissue and liver pathology, as well as in various cellular components of the body. Bcl-2 can form a complex with the voltage-gated anion channel porin (VDAC) on the outer mitochondrial membrane, protecting against cell death by inhibiting the release of cytochrome c
.In Bovine, Bcl-2 contributes to maintaining cell survival, especially in hepatocytes, and is involved in the balance between cell survival and apoptosis, which is crucial for normal physiological processes and disease resistance.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.