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Recombinant Bovine Erythropoietin (EPO), N-His-SUMO
Product Overview
BioVenic's Recombinant Bovine Erythropoietin (EPO), N-His-SUMO is a recombinant protein expressed from E.coli. Its predicted molecular weight is 34.4 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Bovine erythropoietin (EPO) is a glycoprotein hormone primarily produced by the kidneys, known for its crucial role in stimulating red blood cell production. In cattle, EPO not only supports erythropoiesis but also has been discovered to have implications in tissue protection, regeneration, and reproduction. Studies have shown that EPO inhibits cell death by apoptosis and enhances the fertilizing capacity of Bovine spermatozoa by improving sperm motility, viability, and total antioxidant capacity. It also induces sperm capacitation and acrosome reaction, which are essential for sperm to fertilize the oocyte. This suggests a broader physiological role of EPO in reproductive processes beyond its traditional association with erythropoiesis.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.