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Recombinant Bovine Interleukin-5 (IL5), N-His

Cat. No.AP9C349

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Bovine Interleukin-5 (IL5), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 16.7 kDa. The purity is>95% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Bovine
Expression System E.coli
Purity >95% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight 16.7 kDa
Molecular Weight 17 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is 20 mM Tris, 150 mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Target Information

Bovine interleukin 5 (IL-5) is a cytokine that plays a significant role in the immune system of cattle. It is primarily known for its ability to stimulate the growth, differentiation, and activation of eosinophils, which are key cells in allergic reactions and parasitic infections. In cattle, IL-5 contributes to the defense against helminths by promoting eosinophil maturation and function. It also influences B cell differentiation and antibody production, particularly IgA, which is crucial for mucosal immunity. The cytokine helps maintain eosinophil populations and enhances their effector functions, making it an important factor in the inflammatory responses seen in various diseases.

Protein Bovine Interleukin-5 (IL5)
Protein Synonym E-CSF; ESGF; EDF; TRF; Colony-Stimulating Factor,Eosinophil; T-Cell replacing Factor; B Cell Differentiation Factor I; Eosinophil Differentiation Factor
Gene ID 280825
UniProt ID P52173

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.
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