This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Recombinant Bovine Vascular Endothelial Growth Factor D (VEGFCD), N-His
Product Overview
BioVenic's Recombinant Bovine Vascular Endothelial Growth Factor D (VEGFCD), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Bovine vascular endothelial growth factor D (VEGFD) is a member of the platelet-derived growth factor (PDGF)/VEGF family. It is a secreted glycoprotein that plays a significant role in lymphangiogenesis, the formation of new lymphatic vessels. VEGFD is crucial for the development and maintenance of the lymphatic system in cattle. It binds to VEGF receptors, particularly VEGFR-3, to influence lymphatic endothelial cells, promoting their survival, growth, and migration. In cattle, VEGFD is involved in vascular health, immune responses, and is implicated in conditions like lymphedema due to its role in lymphatic function. It also affects blood vessel growth and regulates vascular permeability, making it a significant factor in vascular biology and disease treatment, including potential therapeutic applications for lymphatic drainage disorders and cancer-related lymphatic metastasis.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.