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Recombinant Canine CD274 molecule (CD274), C-Fc
Product Overview
BioVenic's Recombinant Canine CD274 molecule (CD274), C-Fc is a recombinant protein expressed from HEK293 Cell. Its predicted molecular weight is 51.5 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
In canines, the CD274 molecule (also known as PD-L1) is an important immune regulatory protein expressed on T cells, B cells, and tumor cells. It inhibits T-cell activation and cytokine production by binding to PD-1, thus maintaining immune tolerance and preventing autoimmunity. In the tumor microenvironment, CD274 helps tumor cells evade immune surveillance, promoting tumor progression. In veterinary medicine, CD274 is a potential target for cancer immunotherapy, with related antibodies undergoing clinical trials.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.