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Recombinant Canine Interleukin 12 (IL12), C-His

Cat. No.AP1C79

Product TypeAnimal Proteins

Size 25 μg

Product Overview

BioVenic's Recombinant Canine Interleukin 12 (IL12), C-His is a recombinant protein expressed from CHO Cell. Its predicted molecular weight is 23.6 kDa. The purity is>95% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Canine
Expression System CHO Cell
Purity >95% (SDS-PAGE)
Predicted Molecular Weight 23.6 kDa
Physical State Lyophilized
Formulation Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4.

Target Information

Canine IL-12 protein is a heterodimeric cytokine composed of p40 and p35 subunits, which is essential for promoting cell-mediated immune responses. It induces the production of IFN-γ, enhances NK cell cytotoxicity, and increases the mitogenic response of T cells. In dogs, IL-12 is crucial for combating intracellular pathogens, allergic diseases, and neoplasms, and it has been used in gene therapy studies for various types of tumors, either as a single therapeutic approach or in combination with other treatments.

Protein Canine Interleukin 12 (IL12)
Protein Synonym Cytotoxic lymphocyte maturation factor 35 kDa subunit (CLMF p35);
IL-12 subunit p35
Gene names
Gene ID 403977
UniProt ID Q28267

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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