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Recombinant Canine Noggin (NOG)

Name: Recombinant Canine Noggin (NOG)
SKU: AP1C23
Rating: 5 (1 reviews)

Cat. No.AP1C23

Product TypeAnimal Proteins

Size

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Product Overview

BioVenic's Recombinant Canine Noggin (NOG) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 25.1 kDa. The purity is>95% (SDS-PAGE).

Specifications

Type Recombinant Protein

Species Canine

Expression System E.coli

Purity >95% (SDS-PAGE)

Endotoxin < 1 EU/µg

Predicted Molecular Weight 25.1 kDa

Physical State Lyophilized

Formulation The buffer before lyophilization is PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Target Information

Canine noggin is a secreted protein that antagonizes BMP signaling, playing a crucial role in embryonic development and tissue homeostasis. It is involved in the regulation of stem cell proliferation and differentiation, and is essential for proper skeletal and joint formation. Noggin's function is also implicated in maintaining the undifferentiated state of stem cells or directing their differentiation into specific lineages, such as dopaminergic neurons.

Protein Canine Noggin (NOG)

Protein Synonym SYM1; SYNS1; Synostoses(Multiple)Syndrome 1; Symphalangism 1(Proximal)

Gene ID 100683515

UniProt ID A0A8I3P4Q9

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.