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Recombinant Canine Transforming Growth Factor Beta-1 Proprotein (TGFB1), C-His

Cat. No.AP2C50

Product TypeAnimal Proteins

Size 100 μg

Product Overview

BioVenic's Recombinant Canine Transforming Growth Factor Beta-1 Proprotein (TGFB1), C-His is a recombinant protein expressed from HEK293 Cell. Its predicted molecular weight is 43.4 kDa. The purity is>95% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Canine
Expression System HEK293 Cell
Purity >95% (SDS-PAGE)
Predicted Molecular Weight 43.4 kDa
Physical State Lyophilized
Formulation pH 7.4. 5 % trehalose and mannitol are added as protectants.

Target Information

In canines, transforming growth factor beta-1 proprotein (TGFB1) is a multifunctional protein that regulates various cellular processes, including proliferation, differentiation, and apoptosis. It serves as the precursor for both the latency-associated peptide (LAP) and the active TGF-β-1 chain. TGFB1 maintains TGF-β-1 latency in the extracellular matrix and interacts with environmental molecules to control its activation. It plays a crucial role in immune regulation, bone remodeling, and tumor progression. Elevated levels of TGFB1 are often associated with advanced carcinomas and increased tumor invasiveness.

Protein Canine Transforming Growth Factor Beta-1 Proprotein (TGFB1)
Protein Synonym TGFB; TGFBETA1; TGF-BETA1; DPD1; TGFB-1; CED; LAP; TGF-BETA 1; TGFBETA; TGFB1
Gene ID 403998
UniProt ID P54831

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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