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Recombinant Chicken Complement C3,N-His
Product Overview
BioVenic's Recombinant Chicken Complement C3,N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 184.1 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Chicken complement C3 serves as a pivotal protein within the complement system, a crucial aspect of the innate immune response. It participates in all three activation pathways of the complement cascade: the classical, alternative, and lectin pathways. Upon cleavage, C3 generates C3a and C3b, which play specific roles in mediating inflammation and clearing immune complexes. In chickens, C3 facilitates the opsonization of pathogens, enhancing their removal by phagocytic cells, and is instrumental in the assembly of the membrane attack complex, resulting in the lysis of targeted cells.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.