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Recombinant Chicken Fibroblast Growth Factor (FGF4), N-His
Product Overview
BioVenic's Recombinant Chicken Fibroblast Growth Factor (FGF4), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 21.6 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Chicken Fibroblast Growth Factor 4 (FGF4) is a member of the fibroblast growth factor family (FGFs) and is involved in a wide range of processes including embryonic development, cell proliferation, and differentiation. During chicken embryonic development, FGF4 plays a crucial role in limb bud formation and the migration of neural crest cells, acting as a potent chemoattractant to promote cell movement . FGF4 binds to FGF receptors (FGFR) and activates multiple signaling pathways, including RAS/MAPK and PI3K, to regulate cell proliferation and survival. Additionally, FGF4 is expressed during early development and is essential for maintaining the pluripotency and proliferation of embryonic cells. These studies indicate that FGF4 is critical for growth and development in chickens.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.