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Recombinant Chicken Interferon Beta (IFNB), N-His
Product Overview
BioVenic's Recombinant Chicken Interferon Beta (IFNB), N-His is a recombinant protein expressed from E.coli expression system. Its predicted molecular weight is 22.1 kDa. The purity is>95% (SDS-PAGE). The endotoxin level is <1 EU/μg (LAL). It can be used as a positive control or as an immunogen.
Specifications
Target Information
Interferon Beta, encoded by the IFNB gene in chickens, possesses antiviral properties. Unlike chicken IFN-γ, which triggers high levels of nitric oxide production in immune cells, both IFN-λ and IFN-β result in significantly lower levels of nitric oxide in various non-epithelial cell types.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store for 4 weeks at 2-8°C, for 12 months at -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in ddH2O to a concentration of 0.1-0.3 mg/mL. Do not vortex. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
References
- Santhakumar, Diwakar et al. "Avian Interferons and Their Antiviral Effectors." Frontiers in immunology vol. 8 49. 31 Jan. 2017