Recombinant Mouse Nectin-2 (Nectin2), C-Fc

Mouse Nectin-2, or Nectin2, is a cell adhesion molecule involved in cell connections and signaling. In mouse studies, Nectin-2 is explored for its roles in tissue development and cell migration. Nectin-2 belongs to the immunoglobulin superfamily and forms homophilic and heterophilic interactions to mediate cell-cell adhesion. It is crucial for the formation of adherens junctions and the polarization of epithelial cells during tissue morphogenesis. In the nervous system, Nectin-2 plays a role in the development of neural circuits by guiding axon growth and promoting synapse formation. Additionally, Nectin-2 has been implicated in cancer progression, where its dysregulation can lead to increased cell motility and metastasis. The study of Nectin-2 in various developmental processes and disease models helps in understanding the molecular mechanisms underlying tissue architecture and in identifying potential targets for therapeutic interventions in disorders involving abnormal cell adhesion and migration.