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Recombinant Canine NPC Intracellular Cholesterol Transporter 2 (NPC2), N-His

Cat. No.AP9C586

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Canine NPC Intracellular Cholesterol Transporter 2 (NPC2), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 18.0 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Canine
Expression System E.coli
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 18.0 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.

Target Information

Canine epididymal secretory protein E1 (NPC2) is a protein found in the epididymis of dogs, where it plays a crucial role in the maturation and function of sperm cells. NPC2 is involved in the transport of cholesterol within cells, which is essential for maintaining the integrity of the sperm membrane and ensuring the viability of sperm as they travel through the epididymis. This protein may also contribute to the regulation of other lipids, which are important for sperm motility and the acrosome reaction. In the veterinary field, understanding the role of NPC2 can help in the development of treatments for male infertility and in the assessment of sperm health.

Protein Canine NPC Intracellular Cholesterol Transporter 2 (NPC2)
Protein Synonym Epididymal secretory protein E1 (cE1); Niemann Pick type C2 protein homolog
Gene ID 403920
UniProt ID Q28895

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.
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