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Recombinant Mouse TGF-Beta Receptor Type-1 (TGFBR1), C-Fc

Cat. No.AP2C921

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse TGF-Beta Receptor Type-1 (TGFBR1), C-Fc is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 56.2 kDa. The purity is>90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System Human Cells
Purity >90%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 56.2 kDa
Physical State Lyophilized
Formulation 0.01 mol/L PBS (pH 7.2) containing 0.2% (w/v) Procline-300.

Target Information

Mouse TGF-Beta Receptor Type-1 (TGFBR1) is a serine/threonine kinase receptor involved in the TGF-beta signaling pathway. This pathway regulates various cellular processes, including cell growth, differentiation, and apoptosis. TGFBR1 binds to TGF-beta ligands and forms a complex with TGFBR2, initiating signaling cascades that regulate gene expression. TGFBR1 plays a crucial role in immune regulation and tissue homeostasis. Dysregulation of TGFBR1 has been associated with fibrosis, cancer, and immune disorders. Understanding its function may provide insights into developing therapies for these conditions.

Protein Mouse TGF-Beta Receptor Type-1 (TGFBR1)
Protein Synonym ESK2; Transforming growth factor-beta receptor type I; TGF-beta receptor type I
Gene ID 21812
UniProt ID Q64729

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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