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Recombinant Porcine Defensin Beta 2 (DEFb2), N-His-GST
Product Overview
BioVenic's Recombinant Porcine Defensin Beta 2 (DEFb2), N-His-GST is a recombinant protein expressed from E.coli expression system. Its predicted molecular weight is 35.0 kDa. The purity is>80% (SDS-PAGE). The endotoxin level is <1 EU/μg (LAL). It can be used as a positive control or as an immunogen.
Specifications
Target Information
Porcine beta-defensin 2 (PBD-2), a member of the antimicrobial peptide family, is broadly expressed across pig organs and exhibits a wide range of bactericidal activities in vitro. Research indicates that PBD-2 not only protects against bacterial infections through direct bactericidal action but also reduces inflammation by modulating the TLR4/NF-κB pathway.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store for 4 weeks at 2-8°C, for 12 months at -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
References
- Huang, Chao, et al. "Porcine beta-defensin 2 provides protection against bacterial infection by a direct bactericidal activity and alleviates inflammation via interference with the TLR4/NF-κB pathway." Frontiers in Immunology 10 (2019): 1673.