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Mouse Anti-Canine Calpastatin Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine calpastatin. It can be applied to WB, ICC/IF and IHC assays of canine calpastatin.
Specifications
Target Information
Canine calpastatin is the endogenous inhibitor of the calpain protease system, which is crucial in regulating muscle protein degradation. It plays a significant role in maintaining muscle integrity and is hypothesized to influence the expression of calpain system components in skeletal muscle. Nutrition has been shown to affect calpastatin expression, suggesting that dietary interventions could modulate calpain activity in dogs. As calpastatin is the only known specific inhibitor of conventional calpains, it is a key target for therapeutic strategies aimed at managing muscle wasting and diseases associated with calpain overactivity, such as muscular dystrophy in canines.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.