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Mouse Anti-Canine E3 Ubiquitin-Protein Ligase TRIM33 Monoclonal Antibody

Cat. No.VD12N508

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine E3 ubiquitin-protein ligase TRIM33. It is purified by affinity chromatography. It can be applied to WB, IF and IHC assays of canine E3 ubiquitin-protein ligase TRIM33.

Specifications

Application WB; IF; IHC
Clonality Monoclonal
Classification Primary Antibody
Clone M6N14
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine E3 Ubiquitin-Protein Ligase TRIM33
Immunogen Recombinant protein of E3 ubiquitin-protein ligase TRIM33
Purification Purified by Affinity Chromatography
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer 0.1M Tris-Glycine, pH 7.4, with 150 mM NaCl and 50% glycerol
Physical State Liquid

Target Information

Canine TRIM33, also known as TIF1γ or Ectodermin, is an E3 ubiquitin-protein ligase that plays a crucial role in regulating cellular processes such as transcription, cell proliferation, and tumorigenesis. It acts as a tumor suppressor by targeting nuclear β-catenin for degradation, thereby inhibiting Wnt/β-catenin signaling. TRIM33 also regulates TGF-β signaling by promoting SMAD4 ubiquitination and degradation. In canine models, TRIM33 is essential for studying cancer biology and developmental pathways.

Target Canine E3 Ubiquitin-Protein Ligase TRIM33
Gene ID 475804
UniProt ID A0A8C0QN45

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Aizaz, Muhammad, et al. "Genomic analysis, evolution and characterization of E3 ubiquitin protein ligase (TRIM) gene family in common carp (Cyprinus carpio)." Genes 14.3 (2023): 667.
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